HealthFex - INSERM UMRS 1124
Université Paris Cité
45 Rue des Saints Pères
75270 Paris Cedex 06
France
Fax : +33 (0) 1 42 86 20 80
Delphine Meffre
Associate professor, MCU Paris Descartes
Myelination and Nervous system pathologies
delphine.meffre@-Code to remove to avoid SPAM-u-paris.fr
+33 1 42 86 22 73, room H344
Recent Publications
Articles
- Effect of Etazolate upon Cuprizone-induced Demyelination In Vivo: Behavioral and Myelin Gene Analysis.
Carrete A, Padilla-Ferrer A, Simon A, Meffre D, Jafarian-Tehrani M : Neuroscience, 2021 - Mechanical Stretch of High Magnitude Provokes Axonal Injury, Elongation of Paranodal Junctions, and Signaling Alterations in Oligodendrocytes.
Chierto E, Simon A, Castoldi F, Meffre D, Cristinziano G, Sapone F, Carrete A, Borderie D, Etienne F, Rannou F, Morrison B, Massaad C, Jafarian-Tehrani M : Mol Neurobiol, 2018 - A novel model of trauma-induced cerebellar injury and myelin loss in mouse organotypic cerebellar slice cultures using live imaging.
Llufriu-Dabén G, Meffre D, Massaad C, Jafarian-Tehrani M : J Neurosci Methods, 2018 - Involvement of Aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis.
Shackleford G, Sampathkumar NK, Hichor M, Weill L, Meffre D, Juricek L, Laurendeau I, Chevallier A, Ortonne N, Larousserie F, Herbin M, Bièche I, Coumoul X, Beraneck M, Baulieu EE, Charbonnier F, Pasmant E, Massaad C : Proc Natl Acad Sci U S A, 2018 - Targeting demyelination via α-secretases promoting sAPPα release to enhance remyelination in central nervous system.
Llufriu-Dabén G, Carrete A, Chierto E, Mailleux J, Camand E, Simon A, Vanmierlo T, Rose C, Allinquant B, Hendriks JJA, Massaad C, Meffre D, Jafarian-Tehrani M : Neurobiol Dis, 2017 - Liver X Receptors differentially modulate central myelin gene mRNA levels in a region-, age- and isoform-specific manner.
Shackleford GG, Grenier J, Abi Habib W, Massaad C, Meffre D : J Steroid Biochem Mol Biol, 2016 - Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum.
Meffre D, Shackleford G, Hichor M, Gorgievski V, Tzavara ET, Trousson A, Ghoumari AM, Deboux C, Nait Oumesmar B, Liere P, Schumacher M, Baulieu EE, Charbonnier F, Grenier J, Massaad C : Proc Natl Acad Sci U S A, 2015 - Lithium chloride stimulates PLP and MBP expression in oligodendrocytes via Wnt/β-catenin and Akt/CREB pathways.
Meffre D, Massaad C, Grenier J : Neuroscience, 2014 - Wnt and lithium: a common destiny in the therapy of nervous system pathologies?
Meffre D, Grenier J, Bernard S, Courtin F, Dudev T, Shackleford G, Jafarian-Tehrani M, Massaad C : Cell Mol Life Sci, 2013 - Differential regulation of Wnt/beta-catenin signaling by Liver X Receptors in Schwann cells and oligodendrocytes.
Shackleford G, Makoukji J, Grenier J, Liere P, Meffre D, Massaad C : Biochem Pharmacol, 2013 - Lithium enhances remyelination of peripheral nerves.
Makoukji J, Belle M, Meffre D, Stassart R, Grenier J, Shackleford G, Fledrich R, Fonte C, Branchu J, Goulard M, de Waele C, Charbonnier F, Sereda MW, Baulieu EE, Schumacher M, Bernard S, Massaad C : Proc Natl Acad Sci U S A, 2012 - Interplay between LXR and Wnt/β-catenin signaling in the negative regulation of peripheral myelin genes by oxysterols.
Makoukji J, Shackleford G, Meffre D, Grenier J, Liere P, Lobaccaro JM, Schumacher M, Massaad C : J Neurosci, 2011