Recent Publications

Articles

• Targeting the NADPH Oxidase-4 and Liver X Receptor Pathway Preserves Schwann Cell Integrity in Diabetic Mice.
  Eid SA, El Massry M, Hichor M, Haddad M, Grenier J, Dia B, Barakat R, Boutary S, Chanal J, Aractingi S, Wiesel P, Szyndralewiez C, Azar ST, Boitard C, Zaatari G, Eid AA, Massaad C : Diabetes, 2020
• Antidepressive effects of targeting ELK-1 signal transduction.
  Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JP, Grenier J, Ibrahim EC, El Khoury MA, Tse YC, Mongredien R, Barbé A, de Macedo CEA, Jaworski W, Bochereau A, Orrico A, Isingrini E, Guinaudie C, Mikasova L, Louis F, Gautron S, Groc L, Massaad C, Yildirim F, Vialou V, Dumas S, Marti F, Mechawar N, Morice E, Wong TP, Caboche J, Turecki G, Giros B, Tzavara ET : Nat Med, 2018
• Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve.
  Hichor M, Sundaram VK, Eid SA, Abdel-Rassoul R, Petit PX, Borderie D, Bastin J, Eid AA, Manuel M, Grenier J, Massaad C : Sci Rep, 2018
• Liver X Receptors differentially modulate central myelin gene mRNA levels in a region-, age- and isoform-specific manner.
  Shackleford GG, Grenier J, Abi Habib W, Massaad C, Meffre D : J Steroid Biochem Mol Biol, 2016
• Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum.
  Meffre D, Shackleford G, Hichor M, Gorgievski V, Tzavara ET, Trousson A, Ghoumari AM, Deboux C, Nait Oumesmar B, Liere P, Schumacher M, Baulieu EE, Charbonnier F, Grenier J, Massaad C : Proc Natl Acad Sci U S A, 2015
• Lithium chloride stimulates PLP and MBP expression in oligodendrocytes via Wnt/β-catenin and Akt/CREB pathways.
  Meffre D, Massaad C, Grenier J : Neuroscience, 2014
• Wnt and lithium: a common destiny in the therapy of nervous system pathologies?
  Meffre D, Grenier J, Bernard S, Courtin F, Dudev T, Shackleford G, Jafarian-Tehrani M, Massaad C : Cell Mol Life Sci, 2013
• Differential regulation of Wnt/beta-catenin signaling by Liver X Receptors in Schwann cells and oligodendrocytes.
  Shackleford G, Makoukji J, Grenier J, Liere P, Meffre D, Massaad C : Biochem Pharmacol, 2013
• Lithium enhances remyelination of peripheral nerves.
  Makoukji J, Belle M, Meffre D, Stassart R, Grenier J, Shackleford G, Fledrich R, Fonte C, Branchu J, Goulard M, de Waele C, Charbonnier F, Sereda MW, Baulieu EE, Schumacher M, Bernard S, Massaad C : Proc Natl Acad Sci U S A, 2012
• Interplay between LXR and Wnt/β-catenin signaling in the negative regulation of peripheral myelin genes by oxysterols.
  Makoukji J, Shackleford G, Meffre D, Grenier J, Liere P, Lobaccaro JM, Schumacher M, Massaad C : J Neurosci, 2011
• Opposite effects of CBP and p300 in glucocorticoid signaling in astrocytes.
  Fonte C, Trousson A, Grenier J, Schumacher M, Massaad C : J Steroid Biochem Mol Biol, 2007
• Recruitment of the p160 coactivators by the glucocorticoid receptor: dependence on the promoter context and cell type but not hypoxic conditions.
  Trousson A, Grenier J, Fonte C, Massaad-Massade L, Schumacher M, Massaad C : J Steroid Biochem Mol Biol, 2007
• [Unusual mechanism of action and assembly of the glucocorticoid receptor and its coactivators in glial cells].
  Grenier J, Trousson A, Fonte C, Schumacher M, Massaad C : Med Sci (Paris), 2006
• Involvement of {beta}-catenin and unusual behavior of CBP and p300 in glucocorticosteroid signaling in Schwann cells.
  Fonte C, Grenier J, Trousson A, Chauchereau A, Lahuna O, Baulieu EE, Schumacher M, Massaad C : Proc Natl Acad Sci U S A, 2005