HealthFex - INSERM UMRS 1124
Université Paris Cité
45 Rue des Saints Pères
75270 Paris Cedex 06
France
Fax : +33 (0) 1 42 86 20 80
Martine Aggerbeck
CNRS researcher, CR-CNRS
MetaTox
martine.aggerbeck@-Code to remove to avoid SPAM-u-paris.fr
+33 1 76 53 43 55, room P431
Recent Publications
Articles
- The association between environmental exposures to chlordanes, adiposity and diabetes-related features: a systematic review and meta-analysis.
Mendes V, Ribeiro C, Delgado I, Peleteiro B, Aggerbeck M, Distel E, Annesi-Maesano I, Sarigiannis D, Ramos E : Sci Rep, 2021 - A dual mixture of persistent organic pollutants modifies carbohydrate metabolism in the human hepatic cell line HepaRG.
Leblanc AF, Attignon EA, Distel E, Karakitsios SP, Sarigiannis DA, Bortoli S, Barouki R, Coumoul X, Aggerbeck M, Blanc EB : Environ Res, 2019 - Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells.
Attignon EA, Distel E, Le-Grand B, Leblanc AF, Barouki R, de Oliveira E, Aggerbeck M, Blanc EB : Toxicol In Vitro, 2017 - Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells.
Attignon EA, Leblanc AF, Le-Grand B, Duval C, Aggerbeck M, Rouach H, Blanc EB : Arch Toxicol, 2016 - Determination of Heavy Metal Concentrations in Normal and Pathological Human Endometrial Biopsies and In Vitro Regulation of Gene Expression by Metals in the Ishikawa and Hec-1b Endometrial Cell Line.
Guyot E, Solovyova Y, Tomkiewicz C, Leblanc A, Pierre S, El Balkhi S, Le Frère-Belda MA, Lecuru F, Poupon J, Barouki R, Aggerbeck M, Coumoul X : PLoS One, 2015 - Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism.
Ambolet-Camoit A, Ottolenghi C, Leblanc A, Kim MJ, Letourneur F, Jacques S, Cagnard N, Guguen-Guillouzo C, Barouki R, Aggerbeck M : Biochimie, 2015 - Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin.
Pierre S, Chevallier A, Teixeira-Clerc F, Ambolet-Camoit A, Bui LC, Bats AS, Fournet JC, Fernandez-Salguero P, Aggerbeck M, Lotersztajn S, Barouki R, Coumoul X : Toxicol Sci, 2013 - A head and neck cancer tumor response-specific gene signature for cisplatin, 5-fluorouracil induction chemotherapy fails with added taxanes.
Tomkiewicz C, Hans S, Mucchielli MH, Agier N, Delacroix H, Marisa L, Brasnu D, Aggerbeck LP, Badoual C, Barouki R, Aggerbeck M : PLoS One, 2012 - A head and neck cancer tumor response-specific gene signature for Cisplatin, 5-Fluorouracil induction chemotherapy fails with added taxanes.
Tomkiewicz C, Hans S, Mucchielli MH, Agier N, Delacroix H, Marisa L, Brasnu D, Aggerbeck LP, Badoual C, Barouki R, Aggerbeck M : PLoS One, 2012 - The aryl hydrocarbon receptor system.
Barouki R, Aggerbeck M, Aggerbeck L, Coumoul X : Drug Metabol Drug Interact, 2012 - 2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2.
Ambolet-Camoit A, Bui LC, Pierre S, Chevallier A, Marchand A, Coumoul X, Garlatti M, Andreau K, Barouki R, Aggerbeck M : Toxicol Sci, 2010 - Induction of the Ras activator Son of Sevenless 1 by environmental pollutants mediates their effects on cellular proliferation.
Pierre S, Bats AS, Chevallier A, Bui LC, Ambolet-Camoit A, Garlatti M, Aggerbeck M, Barouki R, Coumoul X : Biochem Pharmacol, 2010 - PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes.
Thulin P, Rafter I, Stockling K, Tomkiewicz C, Norjavaara E, Aggerbeck M, Hellmold H, Ehrenborg E, Andersson U, Cotgreave I, Glinghammar B : Toxicol Appl Pharmacol, 2008 - Cytosolic aspartate aminotransferase, a new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedione.
Tordjman J, Leroyer S, Chauvet G, Quette J, Chauvet C, Tomkiewicz C, Chapron C, Barouki R, Forest C, Aggerbeck M, Antoine B : J Biol Chem, 2007 - Cholesteryl ester hydroperoxides increase macrophage CD36 gene expression via PPARalpha.
Jedidi I, Couturier M, Thérond P, Gardès-Albert M, Legrand A, Barouki R, Bonnefont-Rousselot D, Aggerbeck M : Biochem Biophys Res Commun, 2006 - Opposite regulation of the rat and human cytosolic aspartate aminotransferase genes by fibrates.
Tomkiewicz C, Muzeau F, Edgar AD, Barouki R, Aggerbeck M : Biochem Pharmacol, 2004 - Determination of interleukin-4-responsive region in the human cytochrome P450 2E1 gene promoter.
Abdel-Razzak Z, Garlatti M, Aggerbeck M, Barouki R : Biochem Pharmacol, 2004